The first AI-driven simulation tool built specifically for GMP cleanrooms. Optimize layouts, validate zoning, and automate feasibility reports with engineering precision.

Validation Status
ISO 14644 Compliant
Trusted by engineering teams at
Pharma facilities are too complex for intuition. Changes late in the project cost up to 15x more. Our tool replaces manual spreadsheets and assumptions with science-based simulation.
Cleanroom zoning rules are increasingly strict. One error can delay validation by months.
HVAC represents 40–70% of energy costs. Oversizing is wasteful; undersizing is fatal.
Manual feasibility studies take 4-8 weeks. Our AI generates these reports automatically in seconds based on your design.
Accelerate your design process with a streamlined workflow.
Design your facility by drawing rooms and airlocks with advanced intelligent snapping and real-time dimension validation.
Automatically assign ISO cleanliness classes (5/7/8) and configure pressure cascades across your entire facility layout.
Perform instant calculations for airflow volumes, air change rates (ACH), and thermal loads to size your equipment accurately.
Run simulations to automatically detect and highlight potential personnel and material flow conflicts before they become issues.
Instantly generate a comprehensive, regulatory-compliant Feasibility Report powered by AI using all your design and engineering data.





Not a generic CAD tool. Every feature is designed with GMP guidelines and cleanroom physics in mind.
Automatic classification based on process type.
Visual verification of differential pressures across zones.
Early-stage estimation of cooling and heating requirements.
Highlight crossing paths between clean and dirty flows.
Automatically generate reports that meet regulatory standards using AI.
Test multiple layouts side-by-side to find the optimal design.
Join leading pharmaceutical companies, CDMOs, and engineering firms using PharmaTwin.