The first simulation tool built specifically for GMP cleanrooms. Validate zoning, optimize flows, and estimate HVAC loads with engineering precision.

Validation Status
ISO 14644 Compliant
Trusted by engineering teams at
Pharma facilities are too complex for intuition. Changes late in the project cost up to 15x more. Our tool replaces manual spreadsheets and assumptions with science-based simulation.
Cleanroom zoning rules are increasingly strict. One error can delay validation by months.
HVAC represents 40–70% of energy costs. Oversizing is wasteful; undersizing is fatal.
Manual feasibility studies take 4-8 weeks. You need answers in days, not months.
Accelerate your design process with a streamlined workflow.
Draw rooms & airlocks with intelligent snapping.
Auto-assign ISO classes (5/7/8) and pressure cascades.
Instant calculation of airflow, ACH, and thermal loads.
Detect personnel & material flow conflicts automatically.
Export pre-IQ/OQ documentation instantly.





Not a generic CAD tool. Every feature is designed with GMP guidelines and cleanroom physics in mind.
Automatic classification based on process type.
Visual verification of differential pressures across zones.
Early-stage estimation of cooling and heating requirements.
Highlight crossing paths between clean and dirty flows.
Generate PDFs that serve as the foundation for IQ/OQ.
Test multiple layouts side-by-side to find the optimal design.
Join the leading CDMOs and engineering firms using PharmaTwin.